Hexamethonium Dichloride

Hexamethonium dichloride is a quaternary ammonium compound that is composed of the cation hexamethonium and the anion chloride. With the chemical formula C₁₂H₃₀Cl₂N2, it is a white crystalline solid that is highly soluble in water. It is a ganglionic blocking agent that works by blocking the nicotinic acetylcholine receptors in autonomic ganglia, that decreases sympathetic and parasympathetic tone. Hexamethonium dichloride has been used as a pharmaceutical drug in the treatment of hypertension, but its use has declined due to the development of newer and more effective antihypertensive drugs. It is still used in research to study the physiological and pharmacological effects of ganglionic blockade.

FAQ

1. What is dichloride of hexamethonium?

Ans - The chemical formula for the organic compound hexamethonium dichloride is C6H12Cl2. It has a distinctive smell and is a solid white colour. It is employed in the creation of medications and as a pesticide.

2. What is the usage of hexamethonium dichloride?

Ans - Both in the manufacture of pharmaceuticals and as an insecticide, hexamethonium dichloride is employed.

3. What are the potential health hazards of hexamethonium dichloride?

Ans - Hexamethonium dichloride exposure can irritate the skin, eyes, and lungs. Additionally, it may result in headaches, nausea, dizziness, and impaired vision. Hexamethonium dichloride exposure over an extended period of time can harm the kidneys and liver.

4. In what manner should hexamethonium dichloride be kept?

Ans - Storage conditions for hexamethonium dichloride should be cool, dry, and aired. It should not be exposed to direct sunlight and should be kept away from heat and ignition sources.

5. How should hexamethonium dichloride spills be cleaned up?

Ans - Hexamethonium dichloride spills need to be cleaned up right away. Protective clothes, respirators, and the area should be aired and evacuated. With the use of a suitable absorbent substance, the spill should be confined and neutralised. The absorbent material should then be collected and disposed of as hazardous waste.