Pentamethonium Dibromide

Pentamethonium Dibromide

Main Domestic Market All India
Main Export Market(s) Western Europe Central America Australia North America South America Middle East Eastern Europe Asia Africa
Pentamethonium dibromide is a medication that belongs to the class of drugs known as ganglionic blockers. It is used primarily in anesthesia as a muscle relaxant and to lower blood pressure during surgical procedures.

Pentamethonium dibromide works by blocking the activity of ganglionic nicotinic acetylcholine receptors in the autonomic nervous system. This causes a decrease in the activity of both the sympathetic and parasympathetic nervous systems, leading to a decrease in heart rate, blood pressure, and smooth muscle activity.

In addition to its use in anesthesia, pentamethonium dibromide has also been used in the treatment of hypertension, although it has largely been replaced by other medications with fewer side effects. It is not commonly used in clinical practice today.

Pentamethonium dibromide is administered intravenously and is rapidly metabolized and excreted by the kidneys. Side effects can include dry mouth, urinary retention, and decreased gastrointestinal motility. It can also cause a decrease in respiratory function and should be used with caution in patients with respiratory disease.

Overall, pentamethonium dibromide is a medication with a specific set of uses, primarily in anesthesia and as a treatment for hypertension. While it is effective in its intended applications, its side effects and potential for respiratory depression limit its use in clinical practice.



1. Pentamethonium dibromide: What is it?

Ans - A cationic quaternary ammonium salt with the chemical formula (C5H11Br2)+ is pentamethonium dibromide. It is a colourless solid that can be dissolved in polar solvents like water.

2. How is pentamethonium dibromide structured? 

Ans - Five carbon atoms, eleven hydrogen atoms grouped in a ring, and two bromine atoms bound to the carbon atoms make up pentamethonium dibromide.

3. For what purposes is pentamethonium dibromide used?

Ans - Pentamethonium dibromide is a surfactant that is employed in a number of formulations, a food preservative, an antiseptic in cosmetics, and a medicinal.

4. Is it safe to take pentamethonium dibromide?

Ans - When administered at approved dosages, pentamethonium dibromide is usually regarded as a safe substance. When handling the compound, personal protective equipment should be worn and caution should be exercised.

5. How is dibromopentamethonium stored?

Ans - Pentamethonium dibromide should be kept in a firmly closed container and kept in a cool, dry location. It should not be exposed to fire, flame, or harsh sunlight.